What is PRED (Positive Rheotaxis Extended Drop)?

Positive Rheotaxis Extended Drop (PRED) is an innovative sperm selection method that leverages the natural movement of sperm in a microfluidic environment. This technique harnesses the principle of rheotaxis, where sperm cells exhibit a preference for swimming against the flow of fluid, to isolate high-quality sperm for use in assisted reproductive techniques.

How Does PRED Work?

During a PRED procedure, sperm samples are introduced into a microfluidic device designed to mimic the conditions of the female reproductive tract. The microfluidic channels create a controlled flow of fluid, and sperm cells with optimal motility and morphology demonstrate enhanced rheotactic behavior by swimming against the flow and accumulating in specific regions of the device. This selective migration process helps isolate the most viable and functional sperm for use in fertilization procedures.

What are the advantages of PRED in Infertility Treatment?

• Enhanced Sperm Selection: PRED enables the precise selection of high-quality sperm with superior motility and morphology, improving the chances of successful fertilization.
• Minimally Invasive: PRED is a minimally invasive procedure that does not require complex laboratory techniques, making it a safe and efficient option for infertility treatment.
• Increased Fertilization Rates: By isolating the best-performing sperm cells, PRED contributes to higher fertilization rates and improved embryo development in assisted reproductive cycles.
• Personalized Approach: PRED allows for a personalized approach to sperm selection, tailored to each patient’s specific fertility needs and challenges.